Contact Information

Assistant Professor
Department of Psychology
College of Health and Human Sciences
North Carolina A&T State University
1601 E. Market Street
360 Science Bldg
Greensboro, North Carolina 27411

Office 336-285-2273
Fax  336-334-7538

amdevinc@ncat.edu

Membership Information

Membership Category:
Research Scientists

Member Since: 2006

 

Antoniette Maldonado-Devincci, PhD, MA

Antoniette Maldonado-Devincci, PhD, MA

Education

Ph.D. University of South Florida
M.A. University of South Florida
B.A. University of South Florida

Research Statement

My research interests lie broadly in understanding the underlying molecular and neurobiological mechanisms that mediate alcohol-induced changes in brain function and behavior. I am specifically interested in exploring the mechanisms and physiological relevance of alcohol-induced changes in GABAergic neuroactive steroids that may mediate the interaction between alcohol dependence and stress responsivity. Endogenous GABAergic neuroactive steroids contribute to many behavioral and neurobiological effects of alcohol in rodents. In the Neurobehavioral Pharmacology lab, we are investigating whether neuroactive steroids in brain link heavy alcohol drinking with stress and anxiety. We believe that the neuroadaptive changes in neurosteroids contribute to alterations in alcohol drinking brought about by chronic alcohol exposure. We are examining these changes in limbic neurocircuitry in rodent brain utilizing immunohistochemistry and behavioral pharmacology. The overall goal for my research is to identify targets for potential therapeutic intervention to ameliorate or prevent changes in GABAergic neuroactive steroids that may contribute to the development of alcohol use disorders.

View Curriculum Vitae

Recent Publications

Maldonado-Devincci, A.M., Kampov-Polevoi, A., McKinley, R.E., Morrow, D.H., O’Buckley, T.K, and Morrow, A.L.  2016. Chronic intermittent ethanol exposure alters stress effects on (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP) immunolabeling of amygdala neurons in C57BL/6J mice. Frontiers in Cellular Neuroscience, in press.  PMC4777881

Maldonado-Devincci, A.M., Cook, J.B., O’Buckley, T.K., Morrow, D.H., McKinley, R.E., Lopez, M.F., Becker, H.C. and Morrow, A.L.  2014.  Chronic intermittent ethanol exposure and withdrawal alters (3α,5α)-3-hydroxypregnan-20-one immunostaining in cortical and limbic brain regions of C57BL/6J mice.  Alcoholism: Clinical and Experimental Research, 38(10), 2561-2571.  PMC4211975

Maldonado-Devincci, A.M., Beattie, M.C., Morrow, D.H., McKinley, R.E., Cook, J.B., O’Buckley, T.K., and Morrow, A.L.  2014.  Reduction of circulating and selective limbic brain levels of (3α,5α)-3-hydroxypregnan-20-one (3α,5α-THP) following forced swim stress in C57BL/6J mice.  Psychopharmacology, 231, 3281-3292.  PMC4335654

Maldonado-Devincci, A.M., Badanich, K.A., and Kirstein, C.L.  2010.  Alcohol during adolescence selectively alters immediate and long-term behavior and neurochemistry.  Alcohol, 44(1), 57-66.  PMC4199380

Maldonado-Devincci, A.M., Alipour, K.K., Michael, L.A., and Kirstein, C.L.  2010.  Repeated binge ethanol exposure during adolescence enhances voluntary ethanol intake in adulthood in male and female rats.  Pharmacology, Biochemistry and Behavior, 96(4), 476-487. PMC4197847