"Community, Behavioral and Molecular Sciences in Addictive Disorders"

Scientific Program

Wednesday, October 1

7:30 a.m. – 10:00 a.m.

Registration - Haverford Foyer

8:00 a.m. – 8:30 a.m. 

Continental Breakfast & Networking - Haverford Foyer

8:30 a.m. – 8:55 a.m.

Welcome - Haverford Foyer/Baccarat

Welcoming Remarks

Patricia E. Molina, M.D.
Louisiana State University Health Science Center

William Vega, Ph.D.
2008 NHSN Conference Chair
University of California, Los Angeles

Antonio Cepeda-Benito, Ph.D.
Conference Co-Chair & International Chair
Texas A&M University

Lula Beatty, Ph.D.
Chief, Special Populations Office
Office of the Director, National Institute on Drug Abuse

Rebecca Kameny, Ph.D.
The 3-C Institute for Social Development (Cary, NC)
Discussion on the collaboration with NHSN during the conference on developing a customized website as part of an NIMH-funded project. William A. Vega, Ph.D.

8:55 a.m. – 9:25 a.m. 

Conference Theme Overview
Keynote Speaker
Nora D. Volkow, M.D.,
Director, National Institute on Drug Abuse
Imaging Obesity and Addiction

9:30 a.m. – 10:55 a.m. 

Obesity and Addiction

Chair:

Joni Rutter, Ph.D.
National Institute on Drug Abuse

Co-Chairs:

Antonio Cepeda-Benito, Ph.D.
Texas A&M University

William Vega, Ph.D.
University of California, Los Angeles

Presenters:

Luis de Lecea, Ph.D.
Stanford University Medical Center
The Brain Connection: Obesity and Addiction

Roger McIntyre, M.D., FRCPC
University of Toronto
Psychopharmacology Unit, University Health Network
Substance use disorders and overweight/obesity in bipolar I disorder: preliminary evidence for competing addictions

Simon Barquera, MD, MS, PhD.
Universidad Autónoma Metropolitana

Description:

Brain Circuitry involved in natural rewards to motivate behavior overlaps with the neuralcircuitry invoked by addictive drugs to reinforce drug taking. How much the circuits overlap, and to what extent, remains to be determined. Nonethe less, these breain circuits are powerful parts of normal adaptive processes that, when challenged with equally powerful reinforcers (such as drugs of abuse and food), can culminate in loss of control and subsequent addiction or obesity, respectively. Addiction and obesity are mulifactorial disorders, with as much as 40-70% of the vulnerability attributed to genetic differences, indicating a strong biological component. Understanding the biological underpinnings of how these and other psychiatric co-morbidities (such as bipolar disorder) maponto these neural circuits may give insight into more effective treatment and prevention approaches for these disorders. This symposium will examine the links between obesity and addiction from the basic biological, the epidemiologic, and the treatment perspective, with the hope of leveraging the science from one disorder to inform the other.

10:55 a.m. – 11:00 a.m.

3C to Collect Participant Surveys

11:00 a.m. – 11:15 a.m.

BREAK

11:15 a.m. – 12:15 p.m.

Research Priorities and Funding Opportunities at NIDA
(Breakout Sessions) - Haverford Foyer/Baccarat

Co-Chairs:

Ana Anders, L.I.C.S.W.
Office on Special Populations,
National Institute on Drug Abuse

Ivan Montoya, M.D., M.P.H.
Pharmacotherapies and Medical Consequences of Drug Abuse,
National Institute on Drug Abuse

Yonette F. Thomas, Ph.D.
Division of Epidemiology, Services, and Prevention Research,
National Institute on Drug Abuse

Presenters:

Joe Frascella
Clinical Neurosciences (Congressional Room)

Steve Gust
International (Cabinet Suite)

Jag Khalsa
Jacques Normand
Infections (Old Georgetown Room)

Iván Montoya, M.D., M.P.H.
Pharmacotherapies (Haverford/Baccarat)

Lisa Onken, Ph.D.
Behavioral Therapies (Susquehanna/Severn Suite)

Liz Robertson, Ph.D.
Prevention (Executive Boardroom)

Joni Rutter, Ph.D.
Genetics (Judiciary Suite)

Yonette F. Thomas, Ph.D.
Epidemiology (Haverford/Baccarat)

Description:

The purpose of this session is to provide a forum for the meeting participants to convene in small groups with Program staff representing different research areas of NIDA. The goal is to discuss the current lines of research and priorities in specific areas of research, explore potential program relevance of research initiatives of interest of participants, and provide direction about the most pertinent funding mechanisms for potential research proposals. The small group approach will allow a more intimate and in-depth discussion of the research topics of interest, learn from each other’s experiences, and have opportunities for networking and develop research collaborations with others who have similar research interests. Session participants can greatly benefit from the deep knowledge of the current science and research directions that NIDA program officials can offer. It is expected that at the end of the session, participants will be able to have a better understanding of the priorities of NIDA in their areas of research interest as well as the most appropriate opportunities and mechanisms that can be used to apply for funding at NIDA.

12:30 p.m. – 1:50 p.m. 

Mentoring Luncheon (Breakout Sessions)

Session 1:

Mentoring Basic Scientists (Judiciary Suite)

Mentors

Eddie Castañeda, Ph.D.,
University of Texas, El Paso

Keith A. Trujillo, Ph.D.
California State University, San Marcos

Joe L. Martinez, Jr., Ph.D.
University of Texas, San Antonio

Laura Elena O’Dell, Ph.D.
University of Texas, El Paso

Patricia E. Molina, M.D., Ph.D.
Louisiana State University Health Science Center

Description:

This Mentoring Lunch breakout examining mentoring issues in the basic sciences! There are a number of topics from which we will choose to generate constructive discussions, ranging from those specific to basic science, to those more general in nature. What is mentoring? What are mentoring issues specific to the basic sciences? Exactly what are the responsibilities of a mentor? Is mentorship defined by the charge with official responsibility for the work of junior scientists or students? Are there responsibilities outside professional guidance; is personal guidance relevant to effective mentoring? What traits should you seek in finding or being a mentor? How does one define specific goals and measures of accomplishment? As a student (or as a more advanced scientist) how do you get the mentoring you need? What do you do when the relationship is not working out? How do you approach issues related to gender and cultural differences? You should feel welcome to bring other specific questions that can be used for creative discussion.

Session 2:

Developing A Career In Clinical Research (Cabinet Suite)

Mentor:

Iván D. Montoya, M.D., M.P.H.
National Institute on Drug Abuse

Description:

Clinical or patient-oriented research is the medical research conducted with human subjects for which an investigator directly interacts with human subjects. Recent scientific advances are promoting rapid transition from basic to clinical research. Clinical researchers play a critical role in bringing laboratory observations into the clinical settings. This new research paradigm requires an interdisciplinary team approach, with well-trained clinical researchers as integral team members and leaders. An increasing shortage of trained clinical researchers has been widely recognized and documented. The purpose of this session is to discuss the challenges and opportunities in the development of a career in clinical research and to present the efforts and funding opportunities at NIH and NIDA to stimulate clinical research training and career development opportunities.

Session 3:

Funding Mechanisms For Junior Investigators (Old Georgetown Room)

Mentor:

Mimi M. Ghim, Ph.D.
Office of Science Policy and Communications National Institute on Drug Abuse

Description:

NIDA supports a variety of programs designed to attract and develop new and junior investigators in the fields of drug abuse, addiction, and AIDS research. This breakout will provide an overview of these research training and career development programs, which range from NRSA awards for predoctoral and postdoctoral candidates, to mentored career development and research grant awards for newly independent investigators. The process of applying for a training or career development grant at NIDA will also be discussed. In particular, the role of NIDA’s research training committee, program officials, and scientific review officials will be defined. Additional resources to assist with funding and career development will also be shared.

Session 4:

The 5 “P”s Of Publishing: Demystifying Publishing For Early Career Scholars (Susquehanna/Severn Suite)

Mentor:

Liliane Windsor, Ph.D.
Rutgers: The State University of New Jersey

Description:

Presentation argues doctoral students are valuable resources for publishing and contributing to the important task of building bodies of knowledge. Early career scholars are encouraged to collaborate with graduate students in publishing articles. Guidelines for successful publishing are provided, including information on developing collabora tions, identifying publishers, various types of writing within academia, and discussion on obstacles students encounter.

The 5 P’s of Publishing:  Demystifying Publishing for Early Career Scholars

2:00 p.m. – 3:30 p.m. 

Afternoon Breakout Sessions

Session 1:

Alcohol Related Breakout (Congressional Room)
Prevalence, incidence, comorbidity and clinical presentation of alcohol use disorders (AUDs) among Hispanics: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)

Presenters:

Deborah A. Dawson, Ph.D.
Sharon M. Smith, Ph.D.
Bridget F. Grant, Ph.D.
National Institute on Alcohol Abuse and Alcoholism,
National Institutes of Health

Description:

This presentation will briefly summarize the characteristics of Waves 1 and 2 of the NESARC.  It will present prevalence and incidence rates for alcohol abuse and dependence, comparing Hispanics with other major race ethnic groups and making comparisons among different subgroups of Hispanics where possible.  The presentation will also cover comorbidity of AUDs with major mood, anxiety and personality disorders, and examine Hispanic ethnicity in relation to the clinical presentation of AUDs, e.g., age at onset, consumption patterns etc.  Finally, the presentation will touch briefly on the role of acculturation in AUDs among Hispanics.  

Alcohol Related Breakout (continued)

Prevalence, incidence, comorbidity and clinical presentation of alcohol use disorders (AUDs) among Hispanics: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) (Continued)

Alcohol consumption, alcohol problems, Alcohol abuse and dependence among Hispanic national groups.

Presenters: 

Raul Caetano, M.D., Ph.D.
Professor of Epidemiology, University of Texas School of Public Health
Dean, Allied Health Sciences School, University of Texas Southwestern Medical Center

Description:

This presentation will complement the first by presenting data Hispanic patterns of alcohol use and associated problems by national origin group.  The presentation will include findings based on recently collected data from the Hispanic American Baseline Alcohol Survey (HABLAS).  This survey is an NIAAA funded national household population survey of Cuban American, Puerto Rican, Mexican American, Domincan/Central American, and South American Hispanics interviewed in selected geographical areas on the country. Senior staff from the Alcohol Epidemiologic Data  Sysytems (AEDS) will be present to introduce themselves and their role in providing technical assistance and support services to public users of the NIAAA-sponsored NESARC data set.

Session 2:

Basic Science Data Breakout: Datablitz (Cabinet Suite)

Presenters:

Eddie Castañeda, Ph.D.
University of Texas, El Paso

Keith A. Trujillo, Ph.D.
California State University, San Marcos

Description: 

This session will offer NHSN basic scientists the opportunity to share their latest findings with the NHSN community. NHSN members are making exciting discoveries in the basic sciences that expand our understanding of the brain, and of drug abuse and addiction. The goals of this session are to highlight the work of basic scientists who are members of NHSN, and to provide an opportunity for discussion with other scientists with similar interests. 8-10 presentations from NHSN scientists will be selected for a short presentation (up to 3 slides for a 5 minute presentation). In addition to the opportunity to share recent discoveries, it is hoped that exposure to the work of other NHSN basic scientists will facilitate the development of collaborations among NHSN members.

Session 3:

Rethinking Immigration and Drug Use (Old Georgetown Room)

Presenters:

Jorge A. Villatoro Velázquez, Ph.D.
Mexican National Institute of Psychiatry

Juan Carlos Valderrama, M.D., Ph.D.
Generalitat Valenciana

William A. Vega, Ph.D.
UCLA David Geffen School of Medicine

Description: 

More than any other social, political, or economic force, immigration continues to shape the face of the U.S. Immigration and its impact on people’s lives is particularly relevan to Hispanics because Mexico and Spanish-speaking Latin America have dominated U.S. immigration trends since the 1990s—the period of fastest immigration growth in our history. Noting that parallel phenomena are taking place in Spain, the favorite European country for Latin American immigrants, as well as in Mexico and other Latin American countries that receive immigrants from their neighboring countries, US-based and international scientists will explore the implications of current immigration and border issues in drug abuse research and international research collaboration. This breakout is presented by the NHSN’s International Subcommittee.

Session 4:

Item Banking and PROMIS: Advancing the Science of Patient-Reported Outcomes Assessment in Clinical Research (Susquehanna/Severn Suite)

Presenter:

Bryce Reeve, Ph.D.
National Cancer Institute, NIH

Description:

The Patient-Reported Outcomes Measurement Information System (PROMIS) project is supported by a publicly-funded cooperative research group consisting of over 80 investigators from U.S. academic institutions and the National Institutes of Health (NIH). The overall goal for the development of the PROMIS is to provide researchers access to a set of precise, valid, and efficient measures of health-related quality of life (HRQOL) domains. This presentation will review the development of the PROMIS project, the advantages of item banks for use in research, the PROMIS assessment tools that are currently available for researchers, and the future of PROMIS and opportunities for collaboration. Researchers are encouraged to visit the PROMIS website for more information: http://www.NIHpromis.org.

Session 5:

Research in a Global Context (Executive Boardroom)

Presenters:

Jorge Delva, Ph.D.
University of Michigan

Description:

The purpose of this presentation is to discuss three principles that can help increase an investigator’s chances of successfully developing and implementing a funded research project in a global context.  These principles are: (1) Projects should be innovative, build upon the most current scientific knowledge, and include a research capacity development component, (2) projects should be based on strong collaborative, multidisciplinary, partnerships, and (3) project implementation will be most seamless if the sociopolitical, economic, and cultural idiosyncrasies of the countries, collaborators, and study participants are respected and understood.  These principles are discussed in the context of several international projects funded by NIH (e.g., NIDA, NICHD, NIAAA, NHLBI, FIC, & NCMHD).

Session 6:

Translational Research and How to Accelerate it by Engaging Ccommunities:
Goals and Milestones of the NIH CTSA Consortium
(Judiciary Suite)

Co-Chair:

Betty Tai, Ph.D.
National Institute on Drug Abuse

Sergio Aguilar-Gaxiola, M.D., Ph.D.
University of California, Davis

Presenters:

Donna Jo McCloskey, Ph.D.
National Center for Research Resources
Overview of NIH’s Clinical Translational Science Awards (CTSA)

Lloyd Michener, M.D.
Duke University Medical Center
Integrating Practice and Community Programs to Improve Health

Sergio Aguilar-Gaxiola, M.D., Ph.D.
University of California, Davis Health System
Engaging Communities as Partners to Reduce Health Disparities

Description:

A national consortium of 38 medical research institutions, funded through Clinical and Translational Science Awards (CTSAs) by NIH is working together and shares a common vision to improve the way biomedical research is conducted across the country, reduce the time it takes for laboratory discoveries to become treatments for patients, train the next generation of clinical and translational researchers and reach out to and engage communities in clinical research efforts. While the overarching goal of this consortium is to speed the research process so that biomedical discoveries can be translated into clinical practice more quickly, an equally important and significant task is to engage communities in the research process. Community engagement is defined as a multilayered, long-term endeavor that requires academic institutions to think differently about research, and to learn how to build relationships and trust with their local communities. This break-out session will describe the NIH’s CTSA mission and its infrastructure and discuss CTSA’s efforts in engaging communities and community-based practices in accelerating the pace of translational research. Specifically, the invited speakers will provide information to set a platform for further discussion with breakout participants.

3:25 p.m. – 5:30 p.m.  

3C to Collect Participant Survey

3:30 p.m. – 3:45 p.m.  

BREAK

3:45 p.m. – 5:45 p.m.  

National & International Poster Session - Concourse Terrace

Chair:

Nelson Jose Tiburcio, Ph.D.
National Development and Research Institutes

Co-Chairs:

Laura Elena O’Dell, Ph.D.
University of Texas – El Paso

Victoria Ojeda, Ph.D.
Division of International Health & Cross Cultural Medicine, UCSD School of Medicine

Description:

The poster session will bring together national and international posters in one dynamic session, showcasing the work of NHSN members with the goal of creating linkages for both national and international collaboration.

6:00 p.m. – 7:30 p.m

Documentary Film Screening — Haverford/Baccarat

 

Blinded by Open Arm

Blinded by Open Arms is a documentary film that highlights the severe drug and gang problems facing Honduran youth and their families. The youth showcased in the film blame family disintegration as well as poor economic and social conditions as the source of their drug problems and gang related activities. The documentary been accepted at numerous national and international film festivals, including the International Film Festival of England, the International Film Festival of South Africa, and the Artivist Film Festival. The 75 minute film will be followed by a 15 minute discussion led by Alexie Elfmont, the film’s director and producer, as well as by Guillermo Prado, Ph.D., 2008 NHSN Conference Co-Chair.