Sergio Iñiguez, Ph.D.
Ph.D. Florida State University
M.S. California State Univ, San Bernardino
Dr. Iñiguez' research focus is on the developmental neurobiology of mood-related illnesses, such as anxiety and major depressive disorder. To do this, his preclinical research program comprises a multidisciplinary approach (i.e., behavioral, molecular, and pharmacological) to examine how juvenile exposure to stress and/or psychotropic medications (i.e., fluoxetine, ketamine), influence sensitivity to drugs of abuse (i.e., cocaine), as well as memory-related performance, later in life.
Iñiguez SD, Riggs LM, Nieto SJ, Wright KN, Zamora NN, Cruz B, Zavala AR, Robison AJ, Mazei-Robison MS. (2015). Fluoxetine exposure during adolescence increases preference for cocaine in adulthood. Scientific Reports, in press.
Francis TC, Chandra R, Friend DM, Finkel E, Dayrit G, Miranda J, Brooks JM, Iñiguez SD, O’Donnell P, Kravitz A, Lobo MK. (2015). Nucleus accumbens medium spiny neuron subtypes mediate depression-related outcomes to social defeat stress. Biological Psychiatry, 77(3), 212-22. PMID: 25173629.
Iñiguez SD, Riggs LM, Nieto SJ, Dayrit G, Zamora NN, Shawhan KL, Cruz B, Warren BL. (2014). Social defeat stress induces a depression-like phenotype in adolescent male c57bl/6 mice. Stress, 17(3), 247-255.
Iñiguez SD, Alcantara LF, Warren BL, Riggs LM, Parise EM, Vialou V, Wright KN, Dayrit G, Nieto SJ, Wilkinson MB, Lobo MK, Neve RL, Nestler EJ, Bolaños-Guzmán CA. (2014). Fluoxetine exposure during adolescence alters responses to aversive stimuli in adulthood. The Journal of Neuroscience, 34(3), 1007-1021.
Parise EM, Alcantara LF, Warren BL, Wright KN, Hadad R, Sial OK, Kroeck KG, Iñiguez SD, Bolaños-Guzmán CA. (2013). Repeated ketamine exposure induces an enduring resilient phenotype in adolescent and adult rats. Biological Psychiatry, 74(10), 750-759.
Warren BL, Vialou VF, Iñiguez SD, Alcantara LF, Wright KN, Feng J, Kennedy PJ, LaPlant Q, Shen L, Nestler EJ, Bolaños-Guzmán CA. (2013). Neurobiological sequelae of witnessing stressful events in adult mice. Biological Psychiatry, 73(1),7-14.
Iñiguez SD, Charntikov S, Baella SA, Herbert MS, Bolaños-Guzmán CA, Crawford CA. (2012). Post-training cocaine exposure facilitates spatial memory consolidation in c57BL/6 mice. Hippocampus, 22(4), 802-813.
Warren BL, Iñiguez SD, Alcantara LF, Wright KN, Parise EM, Bolaños-Guzmán, CA. (2011). Juvenile administration of concomitant methylphenidate and fluoxetine alters behavioral reactivity to reward- and mood-related stimuli and disrupts ventral tegmental area gene expression in adulthood. The Journal of Neuroscience, 31(28), 10347-10358.