Contact Information

Professor/Director of Proteomic Facility
Universidad Central del Caribe
Department of Microbiology and Immunology
Room 155, Urb. Santa Juanita
Ave. Laurel
Bayamon, PR 00960-6032
United States of America

Office 787 356-9901
Fax 787 740-4300

Membership Information

Membership Category:
Research Scientists

Member Since: 2005


Nawal Boukli, Ph.D.

Nawal Boukli, Ph.D.


Ph.D. Uni. of Geneva, Geneva, Switzerland


View Curriculum Vitae

Recent Publications

Rodríguez, J.W, Rodríguez, L. A, Font. G, Cubano, L. A., Boukli, N. M, Otero, M, Hunter, R, Nair. M. P., and Rios-Olivares, E. (2007). Co-expression of apoptosis related molecules on activated CD8+CD38+ T cells is associated with HIV-1 disease progression. American Journal of infectious diseases Volume 3, Issue 4, p.p. 208-221.

Rodríguez, J.W., Rodríguez, L.A., Font, G., Cubano, L.A., Boukli, N.M., Otero, M., Hunter, Robert, Nair, N.P., Ríos-Olivares, E. (2007). Induction of a Soluble Anti-HIV-1 factor(s) with IFN- , IL-10, and -Chemokine Modulating Activity by an Influenza-Bacterial Polyantigenic Mixture. American Journal of Infectious Diseases. Volume 3, Issue 4, p.p. 266-274.

Cubano, L.A., Sepúlveda-Torres, L Del C, Sosa, G., Boukli, N.M., Robles, R., Rodríguez, J.W., Guzmán, L., and Ríos-Olivares, E. (2008).Prevalence of Drug Resistance and Associated Mutations in a Population of HIV-1+ Puerto Ricans: Gender Variations. Ethnicity & Disease. Volume 18, S2, p.p. 132-136.

Nair, N., Mahajan, S.D., Rodriguez, J.W, Boukli, N.M, Provencio-Vásquez, E., Malow, R.M., and Miguez-Burbano, M.J. (2009). Methamphetamine enhances HIV-1 infectivity inmonocyte-derived dendritic cells. Journal of Neuroimmune Pharmacol. 4(1):129-39.

Boukli N.M., Saiyed, Z.M., Ricaurte, M., Rodriguez, J.W., Rios- Olivares, E., Cubano, L., and Nair, M. (2010). Implications of ER Stress, the Unfolded Protein Response and Pro and Anti-apoptotic Protein Fingerprints in Human Monocyte Derived-Dendritic Cells treated with Alcohol. Alcoholism: Clinical and Experimental Research. Vol. 34, No. 12. December: pp2081-8. PMCID: PMC2988982

Rao, K.V.K, Boukli, N.M., Samikkannu, T, Cubano, L., Dakshayani K.B and Nair, M.P. (2011). Proteomic profiling in PC-3M prostate cancer cell line and cytotoxic effects of cucurma longa. The Open Proteomics Journal. Vol (4):1-11.

Boukli, N.M*., Delgado, B, Ricaurte, M and Espino A.M*. (2011). Fasciola hepatica and Schistosoma mansoni: Identification of Shared Proteins by Comparative Proteomic Analysis. The journal of Parasitology. Vol (97 (5): pp. 852–861, PMID: 21506812. *Seniority of authorship is shared by the first and last authors.

Mazzio, E. A., Boukli, N., Rivera, N. and Soliman, K. F. A. (2012). Pericellular pH homeostasis is a primary function of the Warburg effect: Inversion of metabolic systems to control lactate steady state in tumor cells. Cancer Science, 103: 422–432.

Sepulveda L., De La Rosa A., Cumba L., Boukli, N.M., Ríos-Olivares E., and Cubano, L.A. (2012). Prevalence of Drug Resistance and Associated Mutations in a Population of HIV-1+ Puerto Ricans: 2006 – 2010. AIDS research and treatment.12 pages.
Article ID 934041

Boukli, N.M., Shetty, V., Reis J, Cubano, L., Ricaurte, M., Shah, P., Nickens, Z., Talal, A., Philip, R., and Jain, P. (2012). Unique and Differential Protein Signature for HIV-1 Monoinfection versus co-infection. Clinical Proteomics, 2012. 9:11, 9-11. doi:10.1186/1559-0275

Rao, K.V.K,, Samikkannu, T, Dakshayani B K, Saiyed, Z.M; N, Gandhi, SS Sathaye, MA Indap, Boukli, N.M., Rodriguez, J.W and Nair, M. ( 2012). Combinatorial cytotoxic effects of Curcuma longa and Zingiber officinale on the PC-3M prostate cancer cell line. J Basic Clin Physiol Pharmacol 0(0):1-8 (2012), PMID 23072849

M Powell, Boukli NM, I Almeida, T Perry, T Dye, and S Pratap.. Creation of a Proteomics
and Informatics Collaborative Group to Enhance Biomedical Research at Ethnically Diverse
Institutions. J Biomol Tech. v.23(Suppl); 2012. PMCID: PMC3630554

María T. Miranda, Erick Suárez, Muneer Abbas, Chinea, A, Tosado, R, Ida A Mejías, Boukli, N.M., Dunston G M (2013). HLA class I & II alleles in multiple sclerosis patients from Puerto Rico. Boletin Asoc Med PR Volume 105 (1), 2013. PMID: 23767380

Yang J, Hu D, Xia J, Liu J, Zhang G, Gendelman HE, Boukli, N.M, Xiong H. Enhancement of NMDA Receptor-Mediated Excitatory Postsynaptic Currents by gp120-Treated Macrophages: Implications for HIV-1-Associated Neuropathology (2013). J Neuroimmune Pharmacol. 2013. 8 (4).921-33 PMID: 23660833.PMCID: 3740075.

Berríos, V., Boukli, N., Rodríguez, J.W., Negraes, P., Schwindt, T., Trujilli, C., Cubano, L., Ulrich, H., Ferchmin, P., Eterovic, V., Martins, A. (2015) Paraoxon Interfere with Correct Neural Stem Cell Differentiation. Neurochem Res. 2015 Mar 11. Oct;40(10):2091-101. doi: 10.1007/s11064-015-1548-7. PMID: 25758980

Ricaurte, M., Schizas, N.V., Ciborowski, P and Boukli, N.M (2016). Proteomic analysis of bleached and non-bleached Acropora palmata, a threatened coral species of the Caribbean. Marine pollution bulletin. 2016; 107(1):224-32. PMID: 27105725. *(Corresponding senior author).

Burton LJ, Rivera M, Zou J, Hudson T, Wang G, Zhang, Cubano, L Boukli, N.M*, Odero-Marah, VA*. (2016). Muscadine Grape Skin Extract Induces an Unfolded Protein Response-Mediated Autophagy in Prostate Cancer Cells: A TMT-based quantitative proteomic analysis. PlosOne PloS one. 2016; 11(10):e0164115. PMID: 27755556. PMCID: PMC5068743. *Seniority of authorship is shared by the last two authors.

López, S. N., Rodríguez-Valentín, M., Rivera, M., Rodríguez, M., Babu, M., Cubano, L. A., Wang, G., & Xiong, H., Kucheryavykh, L and Boukli, N.M. (2017). HIV-1 Gp120 clade B/C induces a GRP78 driven cytoprotective mechanism in astrocytoma. Oncotarget. 2017;10.18632/oncotarget;19474. Jul 22;8(40):68415-68438. eCollection 2017 Sep 15. PMID:28978127. PMCID: PMC5620267

Sepúlveda-Torres, L. del C., Rishishwar, L., Rogers, M. L., Ríos-Olivares, E., Boukli, N., Jordan, I. K., & Cubano, L. A. (2017). A decade of viral mutations and associated drug resistance in a population of HIV-1+ Puerto Ricans: 2002–2011. PLoS ONE, 12(5), PMID: 2799893. PMCID: PMC5426751

Rivera M. Ramos M, Rodriguez, M, Lopez S, Cubano, L, Zou J, Zhang Q, Wang G and Boukli, N.M. (2017). Targeting multiple pro-apoptotic signaling pathways with curcumin in prostate cancer cells. PLOS ONE 12(6): e0179587. PMID: 28628644. PMCID: PMC5476315.

Rodriguez, M; Lopez S, M Rivera, LA Cubano, E Ríos and Boukli, N.M. (2018). Natural Polysaccharide Peptide Induces TLR4-Mediated Anti-HIV-1 Response in Human Monocytes. Journal of Immunology Research. Volume 2018, Article ID 8741698, 14 pages.

Valentín-Guillama G, López S, Kucheryavykh YV, Chorna NE, Pérez J, Ortiz-Rivera J, Inyushin M, Makarov V, Valentín-Acevedo A, Quinones-Hinojosa A, Boukli N, Kucheryavykh LY. (2018). Cancers (Basel). 2018 Sep 1;10(9). pi: E301.
5 doi: 10.3390/cancers10090301. PMID: 30200472

J. M. Alves; A H. Martins; C Lameu; T Glaser; Boukli, N.M.; V Bassaneze; R Dariolli; I C. Nascimento; Poliana C.M. Martins; Hellio D. N. de Souza; J E Krieger; D E. Casarini; V M. Sales; J B. Pesquero, Ulrich, H. Kinin-B2 receptor activity in skeletal muscle regeneration and myoblast differentiation. Stem Cell Reviews. 2018 Oct 18. doi: 10.1007/s12015-018- 9850-9.