Marcelo López, Ph.D.
Ph.D. in Psychology, National University of Córdoba, Argentina
M.S. in Psychology, National University of Córdoba, Argentina
B.S. in Psychology, Colegio Nacional de Monserrat Córdoba, National University of Córdoba, Argentina
Since early in my career I have been interested in the effect of environmental factors on voluntary alcohol intake at different stages of development and the learning processes that modulate that interaction. My undergraduate work in Argentina was centered on the effect of alcohol exposure in utero and during early development. When I joined the Center for Drug and Alcohol Programs and the Alcohol Research center at MUSC (Charleston, SC), I continued to evaluate the effect of alcohol and other drugs (i.e. nicotine) during early development. Currently, my work focuses on studying how genetic and environmental factors (e.g. stress) modulate the transition from alcohol use to abuse, and dependence.
Becker HC, Griffin WC, López MF. Neuroadaptive Changes that Result from Chronic Drug Exposure. In: Miller P (Ed.) Encyclopedia of Addictive Behaviors; Biological Research on Addiction: Comprehensive Addictive Behaviors and Disorders, Volume 2. Elsevier, Oxford, U.K., p.169-178, 2013.
Bell RL, López MF, Cui C, Egli M, Johnson KW, Franklin KM, and Becker HC. Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence. Addiction Biology, [Epub ahead of print - Nov 2013]. NIHMSID: 539982
Trantham-Davidson H, Burnett E, Gass JT, López MF, Mulholland PJ, Centanni SW, Floresco S, and Chandler LJ. Chronic alcohol disrupts dopamine receptor activity and the cognitive function of the medial prefrontal cortex. Journal of Neuroscience, 34(10):3706-18, 2014. PMCID: PMC3942586
López MF, Becker HC. Operant ethanol self-administration in ethanol dependent mice. Alcohol, 48(3):295-9, 2014. NIHMSID: 576054. PMCID: PMC4020177
Gass JT, Glen WB Jr, McGonigal JT, Trantham-Davidson H, López MF, Randall PK, Yaxley R, Floresco SB, Chandler LJ. Adolescent Alcohol Exposure Reduces Behavioral Flexibility, Promotes Disinhibition, and Increases Resistance to Extinction of Ethanol Self-Administration in Adulthood. Neuropsychopharmacology.
Antoniette M. Maldonado-Devincci, Jason B. Cook, Todd K. O’Buckley, Danielle H. Morrow, Raechel E. McKinley, Marcelo F. Lopez, Howard C. Becker, and A. Leslie Morrow. Chronic intermittent ethanol exposure and withdrawal alters (3α,5α)-3-hydroxypregnan- 20-one immunostaining in mesocorticolimbic brain regions of C57BL/6J mice. Alcoholism: Clinical and Experimental Research